1496
Juana the Mad Marries Philip the Handsome
The Spanish infanta Juana married the Habsburg archduke Philip in the Low Countries, linking Spain and the Netherlands through the womb of a dynastically pivotal young woman. Their son Charles would inherit Spain, the Netherlands, Austria, and the Holy Roman Empire, becoming the sixteenth century's most powerful monarch. Juana's passionate devotion to Philip would be exploited by her father Ferdinand to question her sanity and justify her imprisonment.
Santo Domingo Founded
Bartholomew Columbus, the admiral's brother, established the first permanent European settlement in the Americas on the south coast of Hispaniola. The town would become the administrative center of Spanish conquest, its cathedral the first in the hemisphere, its forced labor the template for every colonial exploitation to follow. Its grid-plan layout and stone cathedral became the model for every subsequent Spanish colonial capital from Lima to Manila.
Columbus's Second Voyage Ends
The admiral returned from Hispaniola in chains of his own incompetence rather than law. His colony had descended into starvation, mutiny, and mass indigenous killing. Isabella received him coldly. The romantic phase of Spanish exploration was finished; the administrative exploitation phase had begun, and it had already killed tens of thousands of Taino.
Manuel I Expels Jews from Portugal
The Portuguese king, under pressure from his Spanish in-laws, ordered Jews to convert or leave. Many chose conversion under duress; others boarded ships for Morocco, the Ottoman Empire, and the Low Countries. Iberian Jewish life, which had thrived for centuries, was being systematically dismantled in a single generation. The forced conversions created a population of New Christians whose sincerity was perpetually suspected, fueling the Portuguese Inquisition for three centuries.